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Comprehensive overview of COVID-19 clinical trials

Kiran Ejaz1, Tanveer Kauser2, Amnah Siddiqa3

  • 1School of Medicine, Emory University Atlanta, GA, USA.

JPMA. the Journal of the Pakistan Medical Association
|June 10, 2020
PubMed

Insights

Global COVID-19 clinical trials show 1,528 studies, with 940 focusing on medicines and interventions. This research landscape includes pediatric and sex-specific trials, offering diverse therapeutic options for patients worldwide.

Area of Science:

  • Clinical Research
  • Global Health
  • Infectious Diseases

Background:

  • The COVID-19 pandemic necessitated a rapid global research response.
  • Understanding the scope of clinical trials is crucial for identifying treatment gaps and opportunities.

Purpose of the Study:

  • To provide a comprehensive overview of ongoing and concluded COVID-19 clinical trials globally.
  • To categorize trials by intervention type, age group, sex, and geographical location.

Main Methods:

  • A comprehensive search of 16 international trial registries was performed.
  • Data was collected on the total number of trials, participant demographics, and intervention types.

Main Results:

  • Globally, 1,528 COVID-19 trials have been reported, with 940 focusing on medicines and interventions.
  • Fifty trials included pediatric populations, while 18 and 20 trials focused exclusively on females and males, respectively.
  • Notable trial activity includes 2 in Bangladesh, 4 in Pakistan, and 13 in India.

Conclusions:

  • The global landscape of COVID-19 clinical trials is extensive, covering a wide range of interventions.
  • Physicians can leverage this information to identify potentially beneficial trials for their patients.

Keywords:
Coronavirus, 2019-nCoV, SARS-CoV-2, 2019nCoV, Clinical Trial, Asia.

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