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Drug-related Halitosis: A Systematic Review
Oral Health & Preventive Dentistry
|June 10, 2020
Summary
Certain medications can cause extra-oral halitosis, which originates outside the mouth. This review identified 10 medication categories linked to this condition, aiding clinicians in diagnosis.
Area of Science:
- Medical Science
- Pharmacology
- Oral Health
Background:
- Halitosis, or bad breath, can significantly impact individuals.
- Extra-oral halitosis stems from systemic conditions, not oral factors.
- Identifying medication-induced halitosis is crucial for patient care.
Purpose of the Study:
- To systematically review and identify medications causing extra-oral halitosis.
- To categorize the types of drugs associated with this condition.
Main Methods:
- Systematic review adhering to PRISMA guidelines.
- Comprehensive search of online databases and hand searching.
- Independent screening, data extraction, and quality assessment by two authors.
Main Results:
- Thirty-four studies met the inclusion criteria.
- Medications causing extra-oral halitosis were grouped into 10 categories.
- Categories include acid reducers, antidepressants, antifungals, and chemotherapeutics, among others.
Conclusions:
- Pharmaceuticals are a potential cause of extra-oral halitosis.
- Findings assist clinicians in diagnosing the source of halitosis.
- Further research is necessary to fully elucidate medication's role.