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1,2,3,4,-Tetrahydro-1,2-diazepine derivatives: synthesis and evaluation of antileukemic activity
1Dipartimento di Scienze Farmaceutiche, Università di Firenze, Italy.
Il Farmaco; Edizione Scientifica
|November 1, 1988
Abstract:
A series of 3-aryl or etheroaryl-6-cyano-7-phenyl-1,2,3,4-tetrahydro-1,2-diazepin- 5-ones was synthesized and evaluated for its antitumor activity against P388 leukemic tumor system in mice. None of the tested compounds showed significant antitumor properties.