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Updated: Dec 18, 2025

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Published on: June 4, 2015
Identification of Bladder Diverticular Stone on 99mTc-Methyl Diphosphonate Bone Scintigraphy and SPECT/CT
Dania G Malik1, Robert G Ferrigni2, Ming Yang3
1Department of Radiology, Mayo Clinic, Scottsdale, Arizona; and.
Abstract:
We report a bladder diverticular stone with increased 99mTc-methyl diphosphonate uptake on bone scintigraphy and SPECT/CT. Diverticular stone is a known risk factor for bladder malignancy. The deposition of 99mTc-methyl diphosphonate on the crystal surface of the diverticular stone is a rare phenomenon but of clinical significance. Cystolitholapaxy is indicated to remove the diverticular stone and to reduce the risk of bladder cancer.
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