Advances in [4+3]-Annulation/Cycloaddition Reactions Leading to Homo- and Heterocycles with Seven-Membered Rings
Karuppu Selvaraj1, Sachin Chauhan1, K Sandeep1
1School of Chemistry, University of Hyderabad, Hyderabad-500046, Telangana, India.
Abstract:
In this review, we summarize advances in [4+3] and a few other annulation/cycloaddition reactions for the construction of seven membered rings, with an emphasis on the literature subsequent to the year 2010. The type of products include the following: azepines, diazepines, benzazepinones, 1,2-diazepinones, oxazepinones, benzothiazepines, benzodiazepinones, benzoxopinones, cyclohepta[b]indoles, benzoxazepines, azepino-indoles, oxepines/oxazepanes, triazepines oxepinoindolones/azepinoindolones, oxadiazepines, azabicyclooctanes. Emphasis is also given to cover diverse types of annulations; possible intermediates are displayed in the illustrated schemes to aid future work.
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