Fluorinated carbohydrates as chemical probes for molecular recognition studies. Current status and perspectives
Bruno Linclau1, Ana Ardá2, Niels-Christian Reichardt3
1School of Chemistry, University of Southampton, Highfield, Southampton SO171BJ, UK.
Chemical Society Reviews
|June 11, 2020
Abstract:
This review provides an extensive summary of the effects of carbohydrate fluorination with regard to changes in physical, chemical and biological properties with respect to regular saccharides. The specific structural, conformational, stability, reactivity and interaction features of fluorinated sugars are described, as well as their applications as probes and in chemical biology.


