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The most cited articles on cancer immunotherapy: An update study
1Department of Medical Oncology, Cerrahpasa School of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Summary
This study analyzes the development of cancer immunotherapy, highlighting key research trends and influential publications. It identifies significant contributions and breakthroughs in this rapidly evolving field of oncology.
Area of Science:
- Oncology
- Immunology
- Bibliometrics
Background:
- Cancer immunotherapy represents a rapidly advancing field within oncology.
- Understanding the historical development and key trends is crucial for researchers.
- Identifying seminal works aids in navigating this dynamic research landscape.
Purpose of the Study:
- To map the emergence and evolution of cancer immunotherapy research.
- To identify shifting trends and influential publications in the field.
- To provide researchers with easier access to key developments in cancer immunotherapy.
Main Methods:
- A bibliometric analysis of 100 highly cited articles on cancer immunotherapy.
- Data sourced from Thomson Reuters' Web of Science database (2019 query).
- Analysis included topics, journals, authors, institutions, and citation metrics.
Main Results:
- The USA leads in publications, with 2012 being a peak year.
- National Institutes of Health and National Cancer Institute are the most prolific institutions.
- Immune checkpoint inhibitor trials represent highly cited research, with Science and New England Journal of Medicine as leading journals.
Conclusions:
- Cancer immunotherapy is a dynamic and evolving subspecialty in oncology.
- This study highlights significant scientific breakthroughs and landmarks in the field.
- The findings provide a valuable overview of major contributions to cancer immunotherapy research.

