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Updated: Dec 18, 2025

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
The role of anterolateral augmentation in primary ACL reconstruction
David Ferguson1, Rory Cuthbert2, Saket Tibrewal3
1Department of Trauma & Orthopaedic Surgery, Barnet General Hospital, Royal Free Hospitals NHS Foundation Trust, EN5 3DJ, London, UK.
Abstract:
The anterolateral soft tissue envelope of the knee has long been recognised as a key stabilising structure. Once the mainstay of operative management of anterior cruciate ligament (ACL) rupture, interest in the area fell away with the advent of intraarticular arthroscopic reconstruction. Renewed interest in these structures together with cadaveric data evidencing the potential for restoration of near normal knee biomechanics following ACL and anterolateral soft tissue reconstruction has driven current concepts and development of operative techniques. Options for current anterolateral augmentation techniques in primary ACL reconstruction plus patient selection considerations are reviewed, together with an outlook at future research key to development of this area.

