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Percutaneous mitral valve prostheses: 2019 update.

Barbara Bellini1, Antonio Colombo1

  • 1Sezione di Cardiologia Interventistica, Istituto Scientifico San Raffaele, Milano, Italy.

European Heart Journal Supplements : Journal of the European Society of Cardiology
|June 12, 2020
PubMed
Summary
This summary is machine-generated.

Percutaneous mitral valve replacement offers a promising alternative for high-risk patients with severe mitral incompetence. While early mortality remains a concern, ongoing technological advancements suggest improved outcomes for this transcatheter technique.

Keywords:
Mitral valvePercutaneous valve proceduresValve replacement

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Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Biomedical Engineering

Background:

  • Severe mitral incompetence poses significant risks for patients unsuitable for traditional surgery.
  • Transcatheter mitral repair techniques have advanced, but percutaneous mitral valve replacement (PMVR) is emerging as a key alternative.
  • PMVR offers advantages in treating diverse mitral valve anatomies and fully correcting mitral regurgitation.

Purpose of the Study:

  • To review the advancements in percutaneous mitral valve prostheses as an alternative to transcatheter mitral repair.
  • To discuss the development, approaches, and early outcomes of PMVR for severe mitral incompetence.

Main Methods:

  • Review of percutaneous mitral valve prostheses development and their application.
  • Comparison of transapical and transseptal approaches for transcatheter mitral valve procedures.
  • Analysis of early mortality rates and influencing factors in PMVR.

Main Results:

  • Percutaneous mitral valve prostheses have evolved, offering solutions for complex mitral valve anatomies.
  • The transseptal approach is considered the future development path for transcatheter mitral techniques.
  • Early mortality, though decreasing, remains high due to the nascent stage of technology and high-risk patient profiles.

Conclusions:

  • Percutaneous mitral valve replacement is a developing alternative for inoperable patients with severe mitral incompetence.
  • Continued improvements in technology and patient selection are expected to enhance PMVR outcomes.
  • The field anticipates better results in the near future as the technology matures.