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Published on: September 26, 2018
Cardiovascular Prevention: Migrating From a Binary to a Ternary Classification
Amy Lynn Doneen1, Bradley Field Bale1, David John Vigerust2
1College of Medicine, Washington State University, Spokane, WA, United States.
Insights
Shifting from binary to ternary risk assessment enables personalized disease management. This enhanced approach identifies, stabilizes, and regresses atherosclerosis, improving vascular disease understanding and patient care.
Area of Science:
- Cardiovascular Medicine
- Medical Diagnostics
- Inflammation Research
Background:
- Traditional binary risk assessment models have limitations in managing complex diseases.
- Atherosclerosis and vascular disease progression require nuanced understanding beyond standard risk factors.
- Previous research demonstrated the positive impact of evidence-based management on subclinical atherosclerosis.
Purpose of the Study:
- To introduce and advocate for a ternary model of disease identification.
- To demonstrate how this model optimizes individualized disease management.
- To enhance the understanding of atherosclerosis and vascular disease progression.
Main Methods:
- Transitioning from a binary to a ternary approach for disease risk assessment.
- Implementing a redefined disease/inflammatory model for patient management.
- Utilizing comprehensive, evidence-based strategies for atherosclerosis treatment.
Main Results:
- The ternary model facilitates individualized and optimal disease management.
- The redefined approach successfully identifies, stabilizes, and regresses atherosclerosis.
- Enhanced understanding of vascular disease progression is achieved.
Conclusions:
- A ternary model augments, rather than replaces, standard risk factor identification.
- This comprehensive approach benefits individual patient care and disease outcomes.
- Optimized management of atherosclerosis and vascular disease is achievable.
Abstract:
Migrating from a binary approach to risk assessment to a ternary model of disease identification allows for individualized, optimal disease management. Redefining the disease/inflammatory approach has been proven to identify, stabilize, and regress atherosclerosis while adding understanding to the progression of vascular disease. Our previously published results show the beneficial effect of comprehensive, evidence-based management on subclinical atherosclerosis and vulnerable plaque. We argue that this approach does not mitigate the value of utilizing standard risk factor identification, but rather augments it for the benefit of the individual patient.
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