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Related Concept Videos

Cardiovascular Drugs: Classification based on Therapeutic Indications01:18

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Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However,...
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Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
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Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
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Coronary Artery Disease IV: Preventive Measures01:26

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Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
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Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

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Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
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Continuous-time systems have continuous input and output signals, with time measured continuously. These systems are generally defined by differential or algebraic equations. For instance, in an RC circuit, the relationship between input and output voltage is expressed through a differential equation derived from Ohm's law and the capacitor relation,
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Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
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Cardiovascular Prevention: Migrating From a Binary to a Ternary Classification.

Amy Lynn Doneen1, Bradley Field Bale1, David John Vigerust2

  • 1College of Medicine, Washington State University, Spokane, WA, United States.

Frontiers in Cardiovascular Medicine
|June 13, 2020
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Summary

Shifting from binary to ternary risk assessment enables personalized disease management. This enhanced approach identifies, stabilizes, and regresses atherosclerosis, improving vascular disease understanding and patient care.

Keywords:
atherosclerosiscardiovascular disease (CVD)inflammationplaqueprevention

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Area of Science:

  • Cardiovascular Medicine
  • Medical Diagnostics
  • Inflammation Research

Background:

  • Traditional binary risk assessment models have limitations in managing complex diseases.
  • Atherosclerosis and vascular disease progression require nuanced understanding beyond standard risk factors.
  • Previous research demonstrated the positive impact of evidence-based management on subclinical atherosclerosis.

Purpose of the Study:

  • To introduce and advocate for a ternary model of disease identification.
  • To demonstrate how this model optimizes individualized disease management.
  • To enhance the understanding of atherosclerosis and vascular disease progression.

Main Methods:

  • Transitioning from a binary to a ternary approach for disease risk assessment.
  • Implementing a redefined disease/inflammatory model for patient management.
  • Utilizing comprehensive, evidence-based strategies for atherosclerosis treatment.

Main Results:

  • The ternary model facilitates individualized and optimal disease management.
  • The redefined approach successfully identifies, stabilizes, and regresses atherosclerosis.
  • Enhanced understanding of vascular disease progression is achieved.

Conclusions:

  • A ternary model augments, rather than replaces, standard risk factor identification.
  • This comprehensive approach benefits individual patient care and disease outcomes.
  • Optimized management of atherosclerosis and vascular disease is achievable.