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Updated: Dec 18, 2025

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
Published on: February 3, 2023
Dimensional Reduction in Evolving Spin-Glass Model: Correlation of Phenotypic Responses to Environmental and
Ayaka Sakata1, Kunihiko Kaneko2
1Department of Statistical Inference & Mathematics, Institute of Statistical Mathematics, 10-3 Midori-cho, Tachikawa, Tokyo 190-8562, Japan.
Abstract:
The evolution of high-dimensional phenotypes is investigated using a statistical physics model consisting of interacting spins, in which phenotypes, genotypes, and environments are represented by spin configurations, interaction matrices, and external fields, respectively. We found that phenotypic changes upon diverse environmental change and genetic variation are highly correlated across all spins, consistent with recent experimental observations of biological systems. The dimension reduction in phenotypic changes is shown to be a result of the evolution of the robustness to thermal noise, achieved at the replica symmetric phase.
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