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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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Related Experiment Video

Updated: Dec 18, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

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A versatile mouse model of COVID-19

Helene Borrmann¹, Rachel E Rigby¹

¹OxImmuno Literature Initiative, University of Oxford, Oxford, UK. covid19lit@medsci.ox.ac.uk.

Nature Reviews. Immunology

|June 14, 2020

Summary

No abstract available in PubMed .

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