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Related Concept Videos

Dosage Regimens: Designs and Approaches01:28

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Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
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Drug Administration and Therapy Phases: Overview01:26

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Drugs, the chemical agents used in diagnosing, treating, or preventing diseases, undergo a four-phase process of development: pharmaceutic, pharmacokinetics, pharmacodynamics, and therapeutic.
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Understanding drugs, drug products, and their performance in pharmaceutical science is pivotal. Drugs, whether simple molecules or complex compounds, are designed to interact with the body's biological systems to diagnose, treat, or prevent diseases. Drug products include various delivery systems such as tablets, capsules, injections, and inhalers. The performance of these drug products is gauged by their ability to deliver the active ingredient to the desired site of action at the...
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The three-compartment open model is a pharmacokinetic model used to describe the distribution and elimination of drugs following extravascular administration. It comprises a central compartment representing the plasma and two peripheral compartments. The highly perfused peripheral compartment represents organs and tissues with a rich blood supply, such as the liver, kidneys, and lungs. The scarcely perfused peripheral compartment represents tissues with lower blood supply, such as adipose...
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Dosage Interval and Administration Route: Determination Methods01:19

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A medication’s effectiveness largely depends on its appropriate dosage and the route of administration. Dosage ensures that a sufficient drug concentration is maintained in the bloodstream to elicit the desired therapeutic effect without causing toxicity. The route of administration affects the drug's bioavailability, rate of absorption, and onset of action, which are crucial for achieving optimal therapeutic outcomes. Drug dosage calculations are critical to tailoring therapy to...
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Drug Dosage Regimen: Overview01:15

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A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
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A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
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Pharmacy Department management and organization.

Ana Herranz-Alonso1, Carmen Guadalupe Rodríguez-González1, Camino Sarobe-González1

  • 1Servicio de Farmacia, Hospital General Universitario Gregorio Marañón, Madrid. España. aherranza@salud.madrid.org.

Farmacia Hospitalaria : Organo Oficial De Expresion Cientifica De La Sociedad Espanola De Farmacia Hospitalaria
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Summary

Hospital pharmacies adapted to the COVID-19 pandemic by reorganizing services and implementing new strategies. This ensures safe medication use and preparedness for future health crises.

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Area of Science:

  • Health Services Research
  • Hospital Pharmacy Management
  • Infectious Disease Preparedness

Background:

  • The COVID-19 pandemic necessitated rapid hospital service transformations, including increased bed capacity and alternative care sites.
  • Spain experienced a high COVID-19 case count, highlighting the strain on healthcare systems.
  • The need for future pandemic preparedness in hospital pharmacy operations is critical.

Purpose of the Study:

  • To describe organizational changes within the Hospital Pharmacy Department at Hospital General Universitario Gregorio Marañón during the COVID-19 pandemic.
  • To outline strategies for reorganizing hospital pharmacy departments for safe and effective medication use during health crises.
  • To share lessons learned regarding humanization, patient care, and professional well-being in a pandemic context.

Main Methods:

  • Implementation of integral hospital task groups (e.g., COVID-crisis, protocolization, research).
  • Adaptation of internal departmental organization, including management, leadership, and communication plans.
  • Reorganization of processes and focus on staff management and well-being.

Main Results:

  • The hospital pharmacy faced challenges including increased resource demand, evolving therapeutic protocols, and staff strain.
  • New organizational structures and task groups were created to manage pandemic-related demands.
  • Strategies focused on safe medication management, efficient processes, and human-centered care.

Conclusions:

  • Hospital pharmacies require robust organizational strategies to effectively manage pandemics and ensure medication safety.
  • Adaptability in management, communication, and processes is key for hospital pharmacy resilience.
  • Prioritizing people—patients and professionals—is fundamental to humanized healthcare during crises.