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DNA Microarrays

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...

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Related Experiment Video

Updated: Dec 18, 2025

Infinium Assay for Large-scale SNP Genotyping Applications

Infinium Assay for Large-scale SNP Genotyping Applications

Published on: November 19, 2013

Equine Genotyping Arrays.

Robert J Schaefer¹, Molly E McCue²

¹Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, 1365 Gortner Avenue, St Paul, MN 55108, USA.

The Veterinary Clinics of North America. Equine Practice

|June 15, 2020

Summary

This summary is machine-generated.

Equine genotyping arrays have evolved significantly since the horse genome was sequenced, improving genetic research. These tools facilitate cost-effective genotyping and offer insights into horse genomic architecture and function.

Keywords:

Equine GWAS Genotyping array Imputation Population genomics SNP

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Area of Science:

Genomics
Animal Genetics
Equine Science

Background:

Genomic tools are crucial for understanding horse genetic architecture and function.
The equine genetics community actively collaborates on developing genomic resources.
The horse genome sequence (2006) spurred the creation of advanced genotyping arrays.

Purpose of the Study:

To review the design considerations of equine genotyping arrays.
To discuss the selection criteria for genetic variants on these arrays.
To outline current and future applications of equine genotyping arrays.

Main Methods:

Review of historical development of equine genotyping arrays.
Analysis of design considerations and variant selection for each array iteration.
Synthesis of recent and prospective applications.

Main Results:

Multiple generations of high-throughput genotyping arrays have been developed for horses.
Array design evolved based on available genomic data and research needs.
These arrays enable rapid and cost-effective genotyping for various equine studies.

Conclusions:

Equine genotyping arrays are essential tools for advancing horse genetics research.
Continued development and application of these arrays will enhance understanding of equine genomic function.
Future prospects include expanded applications in equine breeding, health, and conservation.