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Updated: Dec 18, 2025

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
Published on: August 8, 2022
Unraveling the Genetics Behind Equid Cardiac Disease
Samantha L Fousse1, Joshua A Stern1
1Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California Davis, Davis, CA, USA; Stern Comparative Cardiac Genetics Laboratory, UC Davis, 2108 Tupper Hall, One Shields Avenue, Davis, CA 95616, USA.
Abstract:
There have been some advances in understanding the genetic contribution to ventricular septal defects in Arabians, sudden death in racehorses, and atrial fibrillation in racehorses. No genetic analyses have been published for aortic rupture in Friesians or atrioventricular block in donkeys despite strong evidence for a genetic cause. To date, no genetic mutation has been identified for any equid cardiac disease. With the advancement of genetic tools and resources, we are moving closer to discoveries that may explain the heritable basis of inherited equid cardiac disease.
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