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Subtypes of the Gc gene (vitamin D binding protein) in the Polish population
D Leśko1, D Schlesinger, J Hałasa
1Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław.
Archivum Immunologiae Et Therapiae Experimentalis
|January 1, 1988
Abstract:
Gc subtypes were analyzed by isoelectric focusing on thin-layer polyacrylamide gel. In the sample of the Polish population including 278 persons, six Gc phenotypes were encountered: 1S, 1F-1S, 1F, 2-1S, 2-1F, 2 with the following frequencies: 0.342, 0.151, 0.014, 0.360, 0.072 and 0.061. Frequency of Gc1S was 0.597, Gc1F - 0.126 and Gc2 - 0.277. It was shown that a group system of the Gc protein in the Polish population was in good agreement with Hardy Weinberg equilibrium.