Related Experiment Video

Updated: Dec 18, 2025

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
08:02

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

4.6K

Allergic Contact Dermatitis in Children: Recommendations for Patch Testing

Idy Tam1,2, JiaDe Yu3,4

  • 1Tufts University School of Medicine, Boston, MA, USA.

Current Allergy and Asthma Reports
|June 18, 2020
PubMed

Insights

Allergic contact dermatitis (ACD) is common in children but often underdiagnosed. Patch testing, the gold standard, is now more standardized for pediatric patients, improving diagnosis and management.

Area of Science:

  • Pediatric Dermatology
  • Allergology
  • Immunology

Background:

  • Allergic contact dermatitis (ACD) affects a significant portion of the pediatric population, yet diagnosis is frequently delayed or missed due to underrecognition.
  • Patch testing is the definitive diagnostic method for ACD in children, but its application presents specific challenges.
  • Limited standardized protocols historically hindered consistent ACD evaluation in pediatric cases.

Purpose of the Study:

  • To review the current literature on allergic contact dermatitis (ACD) in children.
  • To provide an update on the diagnosis and management of pediatric ACD.
  • To discuss the evolving methods and considerations for patch testing in pediatric populations.

Main Methods:

  • Literature review of recent studies on pediatric ACD and patch testing.
  • Analysis of challenges and specialized considerations for patch testing in children.
  • Highlighting the development and utility of a comprehensive pediatric baseline series for patch testing.

Main Results:

  • Recent research underscores the importance of ACD and the effectiveness of patch testing in children.
  • Effective ACD evaluation requires detailed exposure history, judicious allergen selection, and adapted testing techniques for pediatric cooperation.
  • The publication of a standardized pediatric baseline series in 2018 has facilitated more thorough ACD assessments.

Conclusions:

  • Improved diagnostic accuracy for pediatric ACD is achievable with current knowledge and tools.
  • Standardized patch testing protocols are crucial for the effective evaluation and management of ACD in children.
  • This review offers valuable insights for clinicians managing pediatric patients with suspected ACD.
Abstract

Keywords:
Allergic contact dermatitisChildrenPatch testingPediatric

More Related Videos

Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response06:31

Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response

Published on: October 3, 2019

9.0K
Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

7.5K

Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

Overview
31.6K
Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.3K
Hypersensitivities01:30

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
6.0K
Patch Clamp01:18

Patch Clamp

Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...
6.1K