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Related Concept Videos

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Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells
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Brucellosis: An Elusive Backyard Agent.

Zain Rizvi1, Tahir Iqbal1, Haider Bokhary2

  • 1Internal Medicine, Shifa International Hospital, Islamabad, PAK.

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|June 19, 2020
PubMed
Summary
This summary is machine-generated.

Brucellosis, a zoonotic infection, often presents as prolonged fever of unknown origin. This case highlights its diagnosis in a man with persistent pyrexia, confirmed by positive antibody titers.

Keywords:
brucellabrucellosiscontagiousfamily medicineinfectious diseaseinternal medicinemedicinepasteurizationzoonosiszoonotic

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Area of Science:

  • Infectious Diseases
  • Zoonotic Infections
  • Microbiology

Background:

  • Brucellosis is a zoonotic infection caused by Brucella species.
  • Commonly presents as pyrexia of unknown origin with systemic symptoms like night sweats, malaise, arthralgias, and myalgias.
  • Differential diagnosis for prolonged fever is crucial, especially when considering exposure to contaminated food products.

Observation:

  • This report details a case of a male patient presenting with a month-long history of PUO.
  • Enteric fever was excluded, and brucellosis was considered due to clinical suspicion and potential exposure to contaminated food products.

Findings:

  • Blood tests confirmed brucellosis by revealing positive antibody titers.
  • The diagnosis was linked to suspected exposure from inadequate sterilization of food products, indicating a systemic infection.

Implications:

  • This case underscores the diagnostic challenge of brucellosis presenting as PUO.
  • It emphasizes the need for thorough investigation, including serological testing, in endemic areas or with suspected foodborne zoonotic exposure.
  • Highlights public health concerns regarding food safety and sterilization practices.