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The combined effects of mixtures of ionizing radiations
1TRIUMF, University of British Columbia, Vancouver, Canada.
Journal of Theoretical Biology
|October 21, 1988
Abstract:
Ionizing radiation is a special group of toxic agents whose general interaction can be calculated. This was demonstrated using a radiation interaction model previously published. In this paper, this model is refined and mathematically reformulated using a unified set of assumptions. It postulates the existence of a common intermediate lesion and the relative action of lesions before, at and after this common stage. General quantitative dose-effect relationships of mixed radiations can be derived from the dose-effect relationships of the components in the mixture.