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The relative biological effectiveness of the modulated proton beam at TRIUMF
K Nemoto1, T Pickles, A I Minchinton
1Department of Radiology, Tohoku University School of Medicine, Sendai, Japan.
Radiation Medicine
|May 6, 1998
Abstract
Purpose:
The purpose of this study was to determine the relative biological effectiveness (RBE) of proton beam and to study its dependency on fraction number.
Methods:
The relative biological effectiveness (RBE) of fractionated protons compared with 60Co gamma-rays was investigated for the acute mouse skin reaction. The 80 MeV protons generated at the TRIUMF cyclotron were spread out from 7 to 25 mm to irradiate entire legs. One, two, four, and eight fractions were tested.
Results:
RBE values ranged from 1.15 to 1.24 for the acute skin reaction. Fraction dose dependence of RBEs was not observed.