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Published on: November 10, 2017
A carbon nanomaterial derived from a nanoscale covalent organic framework for photothermal therapy in the NIR-II
Qun Guan1, Le-Le Zhou1, Li-Na Zhou1
1College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, P. R. China. yananli@sdnu.edu.cn yubindong@sdnu.edu.cn.
Abstract:
Herein, we report a microporous carbon nanomaterial that was generated from a nanoscale covalent organic framework precursor via a simple pyrolysis approach. The obtained carbon-based nanoparticles possessed a broad NIR absorption capacity and exhibited a high level of photothermal conversion ability (η = 50.6%) in the NIR-II biowindow. Its excellent PTT antitumor efficiency was fully evidenced by in vitro and in vivo experiments under 1064 nm laser irradiation.
