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Updated: Dec 18, 2025

Antibiotic Dereplication Using the Antibiotic Resistance Platform
Published on: October 17, 2019
Recent progress of antibacterial natural products: Future antibiotics candidates
Jiangkun Dai1, Rui Han2, Yujie Xu2
1College of Veterinary Medicine, Northwest A&F University, Shaanxi, China(1); State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macau, China(1); School of Life Science and Technology, Weifang Medical University, Shandong, China(1).
Abstract:
The discovery of novel antibacterial molecules plays a key role in solving the current antibiotic crisis issue. Natural products have long been an important source of drug discovery. Herein, we reviewed 256 natural products from 11 structural classes in the period of 2016-01/2020, which were selected by SciFinder with new compounds or new structures and MICs lower than 10 μg/mL or 10 μM as criterions. This review will provide some effective antibacterial lead compounds for medicinal chemists, which will promote the antibiotics research based on natural products to the next level.
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