Personal activity intelligence and mortality - Data from the Aerobics Center Longitudinal Study

Area of Science:

• Cardiovascular Health
• Preventive Medicine
• Exercise Physiology

Background:

• Personal Activity Intelligence (PAI) is a novel metric translating heart rate data into a weekly score.
• Previous PAI studies were limited to Norwegian populations, questioning generalizability.

Purpose of the Study:

• To investigate the association between PAI and total and cause-specific mortality in a large US cohort.
• To assess the impact of PAI on longevity and cardiovascular disease (CVD) risk.

Main Methods:

• Analysis of the Aerobics Center Longitudinal Study (ACLS), a prospective cohort of 56,175 participants (1974-2002).
• Participants were categorized into 4 weekly PAI groups (0, ≤50, 51-99, ≥100).
• Outcomes assessed included total mortality, CVD mortality, and ischemic heart disease (IHD) mortality over a median 14.9-year follow-up.

Main Results:

• A weekly PAI score of ≥100 was associated with a 21% lower risk of all-cause mortality and a 30% lower risk of CVD mortality compared to inactive individuals (0 PAI).
• Higher PAI scores showed significant reductions in CVD and IHD mortality, particularly in men and women with known CVD risk factors.
• Participants achieving ≥100 PAI weekly lived an average of 4.2 years longer than inactive individuals.

Conclusions:

• PAI is a valuable metric associated with reduced long-term mortality from all causes, CVD, and IHD.
• Recommendations for PAI thresholds can be incorporated into clinical practice and personal health assessments for improved outcomes.
• This study supports the use of PAI for promoting cardiovascular health and longevity in diverse populations.