Related Experiment Video
Updated: Dec 17, 2025

Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator
Published on: May 9, 2014
The next generation of current measurement for ionization chambers
R Fitzgerald1, D E Bergeron1, S P Giblin2
1NIST, USA.
Re-entrant ionization chambers require precise, stable measurements for radionuclide metrology. This study reviews solutions like Ultrastable Low-Noise Current Amplifiers (ULCAs) to address challenges in electronics and source availability.
Area of Science:
- Metrology
- Nuclear Science
- Instrumentation
Background:
- Re-entrant ionization chambers are critical for radionuclide metrology and nuclear medicine.
- High precision (0.1%) and stability over years are required for metrology systems.
- Current measurement linearity from 10⁻¹⁴ A to 10⁻⁸ A is essential.
Purpose of the Study:
- To address challenges of aging electronics and decreasing availability of sealed sources in metrology.
- To review and discuss potential solutions for maintaining and improving ionization chamber capabilities.
- To explore alternative current measurement systems for radionuclide metrology.
Main Methods:
- Review of existing and emerging technologies for current measurement.
- Discussion of ionization chamber design and measurement methodologies.
- Evaluation of Ultrastable Low-Noise Current Amplifiers (ULCAs), resistive-feedback electrometers, and single-electron pumps.
Main Results:
- Ultrastable Low-Noise Current Amplifiers (ULCAs) show significant promise for high-precision measurements.
- Resistive-feedback systems offer a viable alternative, leveraging standard resistor calibrations.
- The study provides a comprehensive overview of potential solutions for metrology challenges.
Conclusions:
- ULCAs and resistive-feedback systems are promising solutions for future radionuclide metrology.
- Addressing electronics aging and source availability is crucial for maintaining metrology standards.
- Continued research in ionization chamber design and measurement techniques is vital.
Related Concept Videos
Controlled-Current Coulometry: Overview
Mass Analyzers: Common Types
Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview
High-Performance Liquid Chromatography: Types of Detectors
Controlled-Current Coulometry: Coulometric Titration
The fundamental requirements for coulometric titrations are (1) 100% efficiency in the reagent-generating electrode reaction and (2) a stoichiometric and preferably rapid reaction between the generated...
Gas Chromatography: Types of Detectors-II

