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Updated: Dec 17, 2025

Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides
Published on: August 20, 2018
Meeting report: 2nd workshop of the peptide ADME discussion group
Anders Sonesson1, Inga Bjørnsdottir2, Jesper Kammersgaard Christensen2
1Department of Bioanalysis, Ferring Pharmaceuticals, Copenhagen, Denmark.
Abstract:
Challenges and opportunities within peptide ADME (absorption, distribution, metabolism and elimination) were presented and discussed at the 2nd workshop of the Peptide ADME Discussion Group in Cambridge, UK (17th of September 2019). This article summarises the presentations and discussions from this workshop. The following topics were covered: Peptide drug-drug interactions (DDIs) Regulatory perspectives on peptide ADME studies Bioavailability of therapeutic peptides impacted by metabolism and oligomerization in the subcutaneous compartment Regulated bioanalysis of parent peptide and active metabolites by immunoaffinity LC-MS/MS Peptide radiopharmaceutical development.
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