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Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
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Pediatric parathyroid disease

Ramin Jamshidi1, J Craig Egan1

  • 1Institutional affiliation: Phoenix Children's Hospital; Departments of Surgery and Child Health, Univeristy of Arizona, Phoenix, AZ; Department of Surgery, Creighton University School of Medicine, Phoenix, AZ; Departments of Surgery and Pediatrics, Mayo Clinic Arizona, Phoenix, AZ.

Seminars in Pediatric Surgery
|June 24, 2020
PubMed

Insights

This review covers parathyroid gland function and disease in children, including rare pediatric conditions like neonatal severe hyperparathyroidism. It details advances in imaging, surgery, and managing low calcium after thyroid surgery.

Area of Science:

  • Pediatric Endocrinology
  • Surgical Endocrinology
  • Calcium Homeostasis

Background:

  • Parathyroid glands regulate calcium and phosphate, crucial for overall health.
  • Parathyroid disease is uncommon in children but presents unique challenges.
  • Understanding pediatric parathyroid disorders is essential for accurate diagnosis and treatment.

Purpose of the Study:

  • To provide a comprehensive review of pediatric parathyroid disorders.
  • To highlight pediatric-specific conditions and considerations.
  • To discuss recent advancements in diagnosis and management.

Main Methods:

  • Literature review focusing on pediatric-specific publications.
  • Synthesis of fundamental parathyroid physiology and pathology.
  • Inclusion of recent advances in imaging, surgical techniques, and complication management.

Main Results:

  • Detailed review of hyperparathyroidism and hypoparathyroidism in pediatric patients.
  • Emphasis on unique pediatric diagnoses, including neonatal severe hyperparathyroidism.
  • Discussion of improved preoperative imaging and intra-operative gland localization.

Conclusions:

  • Pediatric parathyroid disease requires specialized knowledge and approaches.
  • Advances in technology enhance the diagnosis and surgical management of these conditions.
  • Effective management of post-thyroidectomy hypocalcemia is critical in pediatric care.

Keywords:
HyperparathyroidismHypoparathyroidismNeonatal Severe HyperparathyroidismParathyroidParathyroid CarcinomaParathyroid ImagingPost-thyroidectomy Hypocalcemia

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