[Standardised parenteral nutrition in low birth weight preterm newborns: a case report.]

Paolo Galletto1, Daniele Farina1

  • 1SC Neonatologia Ospedale, Presidio Ospedaliero OIRM, Sant'Anna, AOU "Città della Salute e della Scienza di Torino".

Insights

Standardised parenteral nutrition (SPN) can be safely used in neonatal intensive care units, offering consistent nutrient delivery and reducing errors. This case study shows SPN supports regular growth in unstable preterm infants with feeding intolerance.

Area of Science:

  • Neonatal intensive care
  • Parenteral nutrition
  • Pediatric nutrition

Background:

  • Individualized parenteral nutrition (IPN) is prepared by chemists for premature infants during weekdays.
  • Standardised parenteral nutrition (SPN) is currently used for weekend admissions.
  • SPN offers potential benefits including improved nutrient intake, quality control, cost-effectiveness, and reduced errors.

Purpose of the Study:

  • To evaluate the feasibility of increasing the use of SPN as a replacement for IPN in the NICU.
  • To assess the tolerance and growth outcomes of SPN in a case study of a sick, low birth weight infant.

Main Methods:

  • A case study of a sick, low birth weight infant requiring parenteral nutrition.
  • Administration of "ready-to-use" SPN bags from the sixth day of life for thirteen consecutive days.
  • Monitoring of infant growth and tolerance to SPN.

Main Results:

  • The infant experienced regular growth during the SPN administration.
  • The SPN was well tolerated by the infant.
  • No adverse effects were reported during the study period.

Conclusions:

  • Standardised parenteral nutrition is a viable option for neonatal intensive care.
  • SPN can support adequate growth and is well-tolerated in unstable preterm infants.
  • Expanding the use of SPN may enhance efficiency and safety in neonatal nutrition.

Related Concept Videos

Parentral Nutrition: Centeral and Peripheral Parental Nutrition01:27

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
541
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
608
Enteral Nutrition I: Orogastric and Nasogastric Feeding01:26

Enteral Nutrition I: Orogastric and Nasogastric Feeding

Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
938
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
159
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
182
Drug Delivery: Parenteral Route01:29

Drug Delivery: Parenteral Route

The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
1.3K