Related Experiment Video
Updated: Dec 17, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
Covid-19: End of the beginning?
Robert Bergquist1, Anna-Sofie Stengaard2
1Geospatial Health, Ingerod, Brastad. editor@geospatialhealth.net.
Insights
The Coronavirus Disease 2019 (Covid-19) pandemic rapidly spread globally, causing significant public health and economic strain. The disease presents unforeseen effects, highlighting the challenges of managing "known unknowns" and "unknown unknowns".
Area of Science:
- Epidemiology
- Public Health
- Infectious Diseases
Background:
- The emergence of atypical pneumonia cases in China in December 2019, later identified as Coronavirus Disease 2019 (Covid-19).
- The rapid global dissemination of Covid-19, reaching one million cases worldwide within ten weeks.
- The declaration of Covid-19 as a pandemic by the World Health Organization (WHO) on March 11, 2020.
Purpose of the Study:
- To analyze the initial epidemiological trajectory of Covid-19.
- To underscore the profound global impact of the pandemic on public health and the economy.
- To contextualize the unpredictable nature of the disease using the 'known unknowns' and 'unknown unknowns' framework.
Main Methods:
- Retrospective analysis of case data and timelines.
- Review of WHO declarations and case count milestones.
- Qualitative assessment of the pandemic's societal impact.
Main Results:
- Demonstration of exponential growth in Covid-19 cases globally.
- Highlighting the unprecedented speed of pandemic spread.
- Identification of widespread societal and economic disruption.
Conclusions:
- Covid-19 represents a significant global health crisis with far-reaching consequences.
- The pandemic's evolving nature presents ongoing challenges for public health response.
- Effective management requires addressing both predictable and unpredictable aspects of the disease.
Abstract:
The limited case cluster of atypical pneumonia detected in central China in December 2019, now known as Coronavirus Disease 2019 (Covid-19), converted into a million confirmed cases worldwide in only 10 weeks. Declared a pandemic by the World Health Organization (WHO) on 11 March 2020 (WHO, 2020) and passing the 3 million mark on 27 April, the world is under formidable strain with respect to public health, economy and personal life. Time and again we are alerted about unforeseen, new effects of this disease, which brings to mind the terms "known unknowns" and "unknown unknowns" used by former U.S. Secretary of Defense Donald Rumsfield when referring to the lack of evidence of weapons of mass destruction in Iraq ahead of the second Gulf war, a fitting vocabulary as we again are faced with mass destruction, though this time of a different kind.
More Related Videos
Related Concept Videos
Steps in Outbreak Investigation
Stages of Infection
Causality in Epidemiology
Drug Administration and Therapy Phases: Overview
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
Clinical Trials: Overview
Proliferative Phase
Notably, the stratum basale, the basal layer of the endometrium, including the basal parts of the uterine glands, remains unaffected by menstruation. Stem cells in this layer undergo mitosis, regenerating the stratum functionalis and thickening the...

