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Epidural spinal electrical stimulation in severe angina pectoris.
C Mannheimer1, L E Augustinsson, C A Carlsson
1Department of Medicine, Ostra Hospital, Gothenburg, Sweden.
British Heart Journal
|January 1, 1988
Summary
Epidural spinal electrical stimulation improved exercise capacity and reduced angina symptoms in patients with severe angina pectoris. These benefits were observed in addition to optimal pharmacological treatment.
Area of Science:
- Cardiology
- Neuromodulation
- Medical Devices
Background:
- Angina pectoris, particularly functional class III or IV, significantly impacts patient quality of life.
- Optimal pharmacological treatment may not fully alleviate symptoms in all patients.
Purpose of the Study:
- To evaluate the short-term effects of epidural spinal electrical stimulation (ESES) in patients with refractory angina pectoris.
- To assess the impact of ESES on exercise capacity and anginal symptoms.
Main Methods:
- A study involving 10 patients diagnosed with New York Heart Association functional class III or IV angina pectoris.
- Patients received optimal antianginal pharmacological treatment throughout the study.
- Effects of ESES were measured using repeated bicycle ergometer tests.
Main Results:
- ESES significantly increased patients' working capacity.
- ESES led to decreased ST segment depression during exercise.
- ESES increased the time to angina onset and reduced recovery time post-exercise.
Conclusions:
- Epidural spinal electrical stimulation demonstrates short-term efficacy in improving exercise tolerance and reducing angina symptoms.
- The observed benefits of ESES appear independent of changes in myocardial oxygen demand.
- ESES offers an additional therapeutic option for patients with severe angina pectoris unresponsive to pharmacological therapy.