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Related Concept Videos

Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Tumor Immunotherapy01:27

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Targeted Cancer Therapies02:57

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Updated: Dec 17, 2025

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
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Heating technology for malignant tumors: a review.

H Petra Kok1, Erik N K Cressman2, Wim Ceelen3

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International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
|June 25, 2020
PubMed
Summary

Hyperthermia and thermal ablation use heat effectively for cancer treatment. Advanced devices and precise control are crucial for successful thermal therapies, offering local, locoregional, and whole-body options.

Keywords:
HIPECablationheating equipmenthyhperthermiathermal therapy

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Area of Science:

  • Oncology
  • Medical Physics
  • Biomedical Engineering

Background:

  • Heat therapy, including hyperthermia and thermal ablation, is a well-established cancer treatment modality.
  • Effective thermal therapy relies on high-quality equipment, accurate thermal dosimetry, and robust quality assurance.
  • Diverse heating technologies have been developed, varying in technique, depth, focus, and application size.

Purpose of the Study:

  • To provide a comprehensive review of clinical hyperthermia and thermal ablation devices.
  • To outline the proven and experimental clinical applications of thermal therapies.
  • To discuss temperature measurement, treatment planning, and future directions in heating technology for oncology.

Main Methods:

  • Review of existing literature on clinical hyperthermia and ablation devices.
  • Categorization of thermal therapies into local, locoregional, and whole-body approaches.
  • Discussion of various heating modalities including electromagnetic, ultrasonic, perfusion, and conductive methods.

Main Results:

  • Detailed overview of clinically used devices for local (e.g., HIFU, nanoparticle heating), locoregional (e.g., phased array, capacitive systems), and whole-body heating.
  • Compilation of established and investigational clinical applications for hyperthermia and thermal ablation.
  • Exploration of temperature monitoring techniques and treatment planning strategies.

Conclusions:

  • A wide array of thermal therapy devices and techniques are available for cancer treatment.
  • Precise control, accurate dosimetry, and advanced technology are essential for optimizing therapeutic outcomes.
  • Future advancements in heating technology hold significant promise for improving tumor treatment efficacy.