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Actinotignum schaalii Abscess in a Patient with Common Variable Immunodeficiency
Christine Marie Panganiban1, Sudhir Gupta1
1Division of Basic and Clinical Immunology, and Department of Pathology and Laboratory Medicine, University of California at Irvine, Irvine, CA 92660, USA.
Actinotignum schaalii, an anaerobic bacterium, can cause infections beyond the urinary tract, even in immunocompromised patients. Early consideration of this organism in sterile abscesses is crucial for effective treatment.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Medicine
Background:
- Actinotignum schaalii is an anaerobic, gram-positive bacterium commonly found in the urogenital tract.
- It primarily causes urinary tract infections, particularly in elderly individuals.
Observation:
- This report details the first documented case of Actinotignum schaalii infection presenting as cellulitis and abscess.
- The patient had common variable immunodeficiency, a condition affecting the immune system.
Findings:
- The infection was successfully treated with incision and drainage, followed by an extended course of antibiotics.
- This case highlights a rare presentation of Actinotignum schaalii infection.
Implications:
- Actinotignum schaalii should be considered in the differential diagnosis of sterile abscesses.
- Requesting anaerobic cultures is essential when routine cultures yield no growth, aiding in the diagnosis of such infections.
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