Related Experiment Video

Updated: Dec 17, 2025

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

1.7K

Characteristics of Pediatric Glaucoma in a Latin American Reference Center

Catalina Saavedra1, Hernan A Rios1, Sandra Belalcazar2

  • 1Fundación Oftalmológica Nacional, Bogota, Colombia.

Journal of Current Glaucoma Practice
|June 26, 2020
PubMed

Insights

Pediatric glaucoma (PG) is a diverse condition. This study details clinical and epidemiological features of PG in a Latin American reference center, noting a higher frequency of juvenile open-angle glaucoma than previously reported.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Glaucoma Research

Background:

  • Pediatric glaucoma (PG) encompasses a heterogeneous group of ocular disorders.
  • Limited large-scale cohort studies exist due to the low incidence of PG.
  • Understanding PG characteristics is crucial for effective management.

Purpose of the Study:

  • To characterize the clinical and epidemiological profile of pediatric glaucoma patients.
  • To analyze treatment patterns and follow-up data in a national ophthalmologic reference center.
  • To compare findings with existing global literature on pediatric glaucoma.

Main Methods:

  • Retrospective analysis of pediatric glaucoma cases diagnosed between 2005 and 2015.
  • Evaluation of clinical findings, glaucoma type, surgical interventions, and visual acuity outcomes.
  • Inclusion of 89 patients (145 eyes) in the study cohort.

Main Results:

  • Primary PG was the most common type (67.4%), with primary congenital glaucoma (PCG) more prevalent than juvenile open-angle glaucoma (JOAG).
  • Surgical intervention was required in 56.6% of eyes, particularly in PCG (88.4%), while JOAG eyes did not necessitate surgery.
  • Secondary PG cases showed poorer visual acuity outcomes, with only 17.9% maintaining good vision.

Conclusions:

  • The study provides a detailed report on PG characteristics within a Latin American reference center.
  • A higher incidence of JOAG was observed compared to previous reports.
  • Clinical features of PG in this cohort exhibit variations from established international data, highlighting regional differences.
Abstract

Keywords:
Pediatric glaucomaRetrospective studySurgical managementTreatment and follow-up of glaucoma

More Related Videos

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.7K
Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis13:47

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Published on: June 3, 2018

9.7K

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.1K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
873
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.0K
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
145
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
8.4K