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Beta-lactamase-producing bacteria in head and neck infection
1Department of Pediatrics and Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD.
The Laryngoscope
|April 1, 1988
Summary
Beta-lactamase-producing bacteria (BLPB) are common in head and neck infections (HNI), found in over half of patients. This high incidence of BLPB impacts antimicrobial treatment strategies for these common infections.
Area of Science:
- Microbiology
- Infectious Diseases
- Otolaryngology
Background:
- Head and neck infections (HNI) encompass a range of conditions including otitis media, sinusitis, and tonsillitis.
- The increasing prevalence of antibiotic resistance necessitates understanding the microbial landscape of common infections.
Purpose of the Study:
- To investigate the occurrence and types of beta-lactamase-producing bacteria (BLPB) in various head and neck infections.
- To determine the implications of BLPB prevalence on antimicrobial management strategies.
Main Methods:
- Retrospective analysis of bacterial isolates from 513 patients with head and neck infections.
- Identification and characterization of beta-lactamase-producing bacteria, including aerobic and anaerobic species.
Main Results:
- Beta-lactamase-producing bacteria (BLPB) were recovered from 51% of patients with HNI.
- Predominant BLPB included Staphylococcus aureus, Bacteroides melaninogenicus group, and Bacteroides fragilis group.
- Highest recovery rates of BLPB were observed in adenoiditis (85%), adult tonsillitis (82%), and pediatric tonsillitis (74%).
Conclusions:
- Beta-lactamase-producing bacteria are frequently encountered in head and neck infections.
- The high incidence of BLPB suggests a need for careful consideration of antimicrobial selection in treating HNI.