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Assessing Therapeutic Angiogenesis in a Murine Model of Hindlimb Ischemia
Published on: June 8, 2019
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Outcome Of Embolectomy In Patients Presenting Late With Acute Limb Ischemia
Afzal Siddique1, Nauman Imtiaz1, Hafiz Khalid Pervaiz1
1Department of Vascular Surgery, Combined Military Hospital, Rawalpindi, Pakistan.
Journal of Ayub Medical College, Abbottabad : JAMC
|June 26, 2020
Summary
Embolectomy is effective for late-presenting acute limb ischemia in patients with viable limbs, demonstrating a high limb salvage rate. This procedure should be considered for eligible patients presenting with limb ischemia.
Area of Science:
- Vascular Surgery
- Emergency Medicine
- Surgical Outcomes
Background:
- Acute limb ischemia (ALI) presents a significant vascular emergency.
- Delayed presentation of ALI poses challenges for limb salvage.
Purpose of the Study:
- To evaluate the outcomes of embolectomy in patients with late-presenting acute limb ischemia.
- To assess the efficacy and safety of surgical intervention for ALI beyond the typical time window.
Main Methods:
- A cross-sectional descriptive study was conducted.
- Included patients with non-traumatic ALI presenting 6-72 hours post-symptom onset with a viable limb.
- Excluded patients with irreversible ischemia, trauma-related ischemia, or graft occlusion.
Main Results:
- 49 patients (36 male, 13 female) were analyzed.
- 85.7% of limbs were salvaged.
- Complications included fasciotomy (20.4%), re-embolectomy (14.2%), bypass (10.2%), amputations (minor 14.2%, major 10.2%), and death (4%).
Conclusions:
- Embolectomy is an effective treatment for late-presenting acute limb ischemia.
- The procedure offers a viable option for limb salvage in patients with a viable extremity, even with delayed presentation.
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