Pneumococcal superinfection in COVID-19 patients: A series of 5 cases
David Cucchiari1, Juan M Pericàs2, Josep Riera3
1Renal Transplantation Unit, Nephrology Service, Hospital Clinic Barcelona, Spain.
Background:
In the context of the COVID-19 pandemic the risk of misdiagnosis of other causes of respiratory infection is likely. In this work we aim to describe the clinical characteristics, treatment and outcome of pneumococcal infection in COVID-19 patients.
Patients And Methods:
Every COVID-19 patient presenting with concomitant pneumococcal pneumonia during March 2020 in a tertiary teaching Hospital In Barcelona, Spain.
Results:
Five patients with PCR confirmed COVID19 or clinical and radiological suspicion were diagnosed of pneumococcal infection. In all cases chest X-ray were abnormal, with unilateral or bilateral infiltrates. Procalcitonin showed to be not sensitive enough to detect pneumococcal infection. Antibiotherapy was promptly started in all five cases with subsequent satisfactory evolution.
Conclusion:
International guidelines do not include the universal screening for bacterial co-infection. Radiological pattern of COVID-19 can be indistinguishable from that of pneumococcus pneumonia and frequency of co-infection is not well stablished, therefore clinicians should be aware of the possible SARS-CoV-2-pneumococcus association to avoid misdiagnosis and delay antibiotic therapy.
Insights
Pneumococcal infection can co-occur with COVID-19, potentially leading to misdiagnosis. Early antibiotic treatment for bacterial pneumonia in COVID-19 patients is crucial for favorable outcomes.
Area of Science:
- Infectious Diseases
- Pulmonology
- Internal Medicine
Background:
- The COVID-19 pandemic presents diagnostic challenges for respiratory infections.
- Distinguishing between COVID-19 and other causes like pneumococcal pneumonia is critical.
Observation:
- This study observed five patients with confirmed or suspected COVID-19 and pneumococcal pneumonia.
- Chest X-rays showed abnormal unilateral or bilateral infiltrates in all cases.
- Procalcitonin levels were not sensitive enough for diagnosing pneumococcal infection.
Findings:
- All patients received prompt antibiotic therapy.
- Satisfactory clinical evolution was noted in all treated cases.
- Radiological findings of COVID-19 and pneumococcal pneumonia can be similar.
Implications:
- Clinicians must consider the possibility of SARS-CoV-2 and pneumococcus co-infection.
- Universal screening for bacterial co-infections is not standard but may be warranted.
- Awareness of this association can prevent misdiagnosis and delayed treatment.
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