Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

8.8K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
8.8K
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

178
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
178
Applications Of NMR In Biology01:25

Applications Of NMR In Biology

4.3K
Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
4.3K
Proteomics01:33

Proteomics

9.1K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
9.1K
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

246
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
246

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Application of voxel-wise SAR efficiency to evaluate suitability of novel materials in MRI with parallel transmit.

Physics in medicine and biology·2026
Same author

Multifunctional Magnetic Resonance Imaging Probes.

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer·2026
Same author

Cross-Site Generalization of CNN-Based <math><semantics><mrow><msubsup><mi>B</mi> <mn>1</mn> <mo>+</mo></msubsup></mrow> <annotation>$$ {B}_1^{+} $$</annotation></semantics></math> Mapping in UHF MRI.

NMR in biomedicine·2026
Same author

Chemical exchange saturation transfer (CEST) imaging reveals tumor-specific molecular changes in adult gliomas after radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same author

Assessment of multimodal CEST, perfusion and diffusion MRI for predicting clinical outcome of patients with diffuse glioma following surgery at baseline before radiotherapy.

Cancer imaging : the official publication of the International Cancer Imaging Society·2026
Same author

Navigator-Based Slice Tracking for Multiband Accelerated Liver DWI.

Magnetic resonance in medicine·2026

Related Experiment Video

Updated: Dec 17, 2025

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
09:08

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging

Published on: February 27, 2011

16.2K

Multifunctional Magnetic Resonance Imaging Probes.

Philipp Biegger1, Mark E Ladd1,2,3, Dorde Komljenovic4

  • 1Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer
|June 29, 2020
PubMed
Summary
This summary is machine-generated.

Multifunctional magnetic resonance (MR) imaging probes offer advanced cancer diagnostics and therapy. Innovations in nanoparticulate probes show promise for clinical oncology, though sensitivity remains a challenge.

Keywords:
GadoliniumIron oxideLanthanidesMagnetic resonance imagingMultifunctional imaging probesMultimodal imagingTheranostics

More Related Videos

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
07:01

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Published on: June 9, 2016

9.9K
Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

10.6K

Related Experiment Videos

Last Updated: Dec 17, 2025

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
09:08

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging

Published on: February 27, 2011

16.2K
Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
07:01

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Published on: June 9, 2016

9.9K
Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

10.6K

Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Oncology

Background:

  • Magnetic resonance imaging (MRI) offers high spatial resolution and soft tissue contrast, crucial for cancer assessment.
  • Recent advancements in intrinsic and extrinsic MRI probes enhance its role in preclinical and translational cancer research.
  • Nanoparticulate probes with chemical modifications are emerging as versatile tools for cancer diagnostics and therapeutics.

Purpose of the Study:

  • To summarize innovations in multifunctional MRI probes for oncology.
  • To discuss the clinical applicability and transferability of advanced MRI probes.
  • To highlight the potential of these probes in diagnostics, therapy, and theranostics.

Main Methods:

  • Review of recent literature on multifunctional and multimodal MRI imaging probes.
  • Analysis of chemical modifications and nanoparticulate probe development.
  • Assessment of probe sensitivity, specificity, and clinical translation potential.

Main Results:

  • Numerous preclinical multimodal/multifunctional MRI probes have been developed, primarily as proof-of-concept studies.
  • These probes offer potential for enhanced diagnostics, targeted drug delivery, and theranostics.
  • A limited number of advanced probes are currently suitable for clinical application.

Conclusions:

  • Multifunctional MRI probes represent a significant advancement in cancer imaging and treatment.
  • Further development is needed to overcome sensitivity limitations and facilitate clinical translation.
  • Nanoparticulate probes hold substantial promise for the future of human oncology.