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Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Applications Of NMR In Biology01:25

Applications Of NMR In Biology

Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
The...

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Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
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Published on: June 9, 2016

Multifunctional Magnetic Resonance Imaging Probes.

Dorde Komljenovic1,2, Philipp Biegger3, Helen Abeln3,4

  • 1Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany. dorde.komljenovic@dkfz-heidelberg.de.

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer
|May 18, 2026
PubMed
Summary
This summary is machine-generated.

Multifunctional magnetic resonance (MR) imaging probes enhance cancer assessment. Innovations focus on combining diagnostics and therapy for improved clinical translation, addressing MR imaging

Keywords:
GadoliniumIron oxideLanthanidesMultifunctional imaging probesMultimodal imagingTheranosticsMagnetic resonance imaging

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Last Updated: May 19, 2026

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Published on: June 9, 2016

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09:08

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging

Published on: February 27, 2011

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

Area of Science:

  • Biomedical Engineering
  • Medical Imaging
  • Nanotechnology

Background:

  • Magnetic resonance imaging (MRI) offers high spatial resolution and soft tissue contrast.
  • Development of intrinsic and extrinsic MR imaging probes has advanced cancer assessment in preclinical and translational research.
  • Nanoparticulate probes with chemical modifications offer potential for multifunctional tools in oncology.

Purpose of the Study:

  • To summarize recent innovations in multifunctional MR imaging probe development.
  • To discuss the clinical applicability and transferability of these advanced probes.
  • To highlight the potential of multifunctional probes for diagnostics, therapy, and theranostics in human oncology.

Main Methods:

  • Review of recent literature on the development and characterization of multifunctional MR imaging probes.
  • Analysis of chemical modifications and nanoparticulate probe designs.
  • Evaluation of probe suitability for clinical translation based on preclinical and translational studies.

Main Results:

  • Numerous preclinical multimodal or multifunctional imaging probes have been developed, primarily as proof-of-principle studies.
  • A limited number of these advanced probes are currently applicable in clinical settings.
  • Multifunctional probes offer advantages such as combined diagnostic and therapeutic capabilities (theranostics).

Conclusions:

  • Multifunctional MR imaging probes represent a significant advancement in oncology, offering enhanced diagnostic and therapeutic potential.
  • Further research and development are needed to bridge the gap between preclinical proof-of-concept and clinical application.
  • The clinical transfer of these innovative probes holds promise for improving cancer management.