Related Experiment Video
Updated: Dec 17, 2025
Lethality Bioassay Using Artemia salina L.
Published on: October 11, 2022
Artemyrianins A-G from Artemisia myriantha and Their Cytotoxicity Against HepG2 Cells
Shuang Tang1,2, Yun-Bao Ma1, Chang-An Geng1
1State Key Laboratory of Phytochemistry and Plant Resources in West China, Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, People's Republic of China.
Abstract:
Four new sesquiterpenoids, artemyrianins A-D (1-4), and three new norlignans, artemyrianins E-G (5-7), together with five known compounds (8-12), were isolated from the aerial parts of Artemisia myriantha (Asteraceae). The new compounds were established by spectroscopic data analyses (HRMS, IR, 1D and 2D NMR), and their absolute configurations were confirmed by the single-crystal X-ray diffraction or ECD calculations. The isolates showed cytotoxicity against HepG2 cells with IC50 values ranging from 33.3 to 145.2 μM.
