Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Reactive arthritis associated with Clostridium difficile enteritis.

M H Atkinson1, B D McLeod

  • 1University of Calgary Rheumatic Disease Unit, Calgary General Hospital, Canada.

The Journal of Rheumatology
|March 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Motivation and treatment credibility predict alliance in cognitive behavioral treatment for youth with anxiety disorders in community clinics.

Journal of clinical psychology·2017
Same author

ACP Journal Club: combination intensive DMARD therapy is noninferior to TNF inhibitors for reducing disability in active RA.

Annals of internal medicine·2015
Same author

Osteoarthrosis.

Canadian family physician Medecin de famille canadien·2011
Same author

Nonarticular rheumatism.

Canadian family physician Medecin de famille canadien·2010
Same author

An evidence-based approach to prescribing NSAIDs in musculoskeletal disease: a Canadian consensus. Canadian NSAID Consensus Participants.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·1996
Same author

The role of viscosupplementation with hylan G-F 20 (Synvisc) in the treatment of osteoarthritis of the knee: a Canadian multicenter trial comparing hylan G-F 20 alone, hylan G-F 20 with non-steroidal anti-inflammatory drugs (NSAIDs) and NSAIDs alone.

Osteoarthritis and cartilage·1995
Same journal

Clinical Features and Outcome Measures Across Still Disease (Systemic Juvenile Idiopathic Arthritis and Adult-Onset Still Disease) Cohorts Worldwide: A Systematic Literature Review.

The Journal of rheumatology·2026
Same journal

Concurrent Calcium Pyrophosphate Deposition Disease and Gout of the Cervical Spine Presenting With Subacute Neck Pain and Radiculopathy.

The Journal of rheumatology·2026
Same journal

The Need for Weight Communication Guidelines in Pediatric Rheumatology.

The Journal of rheumatology·2026
Same journal

Bimekizumab Improves Health Status and Work Productivity, With Reduced Productivity Costs, to 3 Years in Axial Spondyloarthritis and Psoriatic Arthritis.

The Journal of rheumatology·2026
Same journal

Qualitative Analysis of Physical Activity Engagement in Women with Self-Reported SLE: The Role of Symptoms, Healthcare Providers, and the Environment.

The Journal of rheumatology·2026
Same journal

Tumoral Calcinosis-like Calcification of the Proximal Interphalangeal Joint Mimicking Rheumatoid Arthritis Flare.

The Journal of rheumatology·2026
See all related articles

Reactive arthritis can occur after Clostridium difficile infection in adults. This study found a benign course for this joint complication, even without typical reactive symptoms.

Area of Science:

  • Rheumatology
  • Infectious Diseases
  • Microbiology

Background:

  • Clostridium difficile infection (CDI) is a significant cause of infectious diarrhea.
  • Reactive arthritis is a form of inflammatory arthritis that can be triggered by infections elsewhere in the body.

Observation:

  • Two adult patients developed reactive arthritis following enteric Clostridium difficile infection.
  • Neither patient exhibited other common reactive arthritis symptoms like conjunctivitis, mucous membrane lesions, or urethritis.
  • One patient was positive for the HLA-B27 antigen.

Findings:

  • Reactive arthritis following CDI presented with peripheral joint involvement in the observed cases.
  • The arthritis followed a benign, short-term course in both patients.

Related Experiment Videos

  • Review of three additional cases of C. difficile-associated arthritis supports these observations.

    • Implications:

    • Clostridium difficile infection should be considered as a potential trigger for reactive arthritis, particularly in adults.
    • The absence of classic reactive symptoms does not rule out this diagnosis.
    • Further research is warranted to understand the pathogenesis and long-term outcomes of C. difficile-associated reactive arthritis.