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Updated: Dec 17, 2025

Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization
Published on: August 11, 2023
Alexandrite Laser-Induced Choroidal Neovascularization Successfully Treated With Aflibercept
Asterios Diafas1, Despoina Stampouli2, Anna Dastiridou1
1Ophthalmology, Papageorgiou General Hospital / Aristotle University of Thessaloniki, Thessaloniki, GRC.
Abstract:
A 33-year-old female was referred to the ophthalmology department after an accidental eye injury to her right eye during a hair removal session using alexandrite laser. Although she initially experienced no symptoms, when re-examined one and a half months later the best-corrected visual acuity (BCVA) of the affected eye was 20/40 secondary to choroidal neovascularization confirmed by fluorescein angiography (FA) and optical coherence tomography (OCT). Intravitreal anti-vascular endothelial growth factor (VEGF) therapy (three monthly injections of aflibercept) led to complete regression of the neovascularization and functional recovery which was maintained at one-year follow-up post original injury.
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