Related Experiment Video
Updated: Dec 17, 2025

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
The diagnostic yield of urgent colonoscopy in acute lower gastrointestinal bleeding
M Mosli1, A Aldabbagh2, H Aseeri1
1Department of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Insights
Urgent colonoscopy for lower gastrointestinal bleeding (LGIB) did not improve bleeding source identification or patient outcomes. Early colonoscopy was unexpectedly linked to a higher colectomy rate.
Area of Science:
- Gastroenterology
- Endoscopy
- Colorectal Surgery
Background:
- Lower gastrointestinal bleeding (LGIB) is a common reason for emergency room visits.
- Colonoscopy is standard for LGIB, but optimal timing is debated.
- The benefit of urgent endoscopic evaluation for LGIB outcomes is unclear.
Purpose of the Study:
- To evaluate the effectiveness of urgent colonoscopy in identifying the source of LGIB.
- To determine if urgent colonoscopy impacts colectomy or mortality rates.
Main Methods:
- Retrospective study of 183 patients undergoing colonoscopy for LGIB.
- Colonoscopies categorized as urgent (within 24 hours) or delayed (>24 hours).
- Analysis of clinical data, endoscopic findings, and outcomes including colectomy and mortality.
Main Results:
- A source of LGIB was identified in 55.7% of first-attempt colonoscopies.
- Urgent colonoscopy (55.4% of cases) did not improve bleeding source identification (RR 1.01).
- Urgent colonoscopy was associated with a higher colectomy rate (RR 4.8) and predicted colectomy need.
Conclusions:
- Urgent colonoscopy for LGIB does not enhance the identification of bleeding sources.
- Early colonoscopy did not reduce colectomy or mortality rates in LGIB patients.
- Timing of colonoscopy and patient age were predictors of colectomy necessity.
Background And Aims:
Lower Gastrointestinal Bleeding (LGIB) is one of the leading causes of ER visits. Colonoscopy is indicated in all patients with LGIB, yet the time frame for performing colonoscopy remains unclear. Whether or not urgent endoscopic evaluation improves outcomes of LGIB has been questioned. We therefore aimed to examine the success of urgent colonoscopy in identifying the source of LGIB.
Patients And Methods:
A retrospective study was conducted in which timing of colonoscopy was divided into urgent (performed within the first 24 hours of presentation) and delayed (performed following 24 hours of hospitalization). Data on clinical presentation, investigations and endoscopic findings was collected. Risk ratios were calculated and regression analysis was used to examine associations and identify predictors of endoscopic success.
Result:
A total of 183 patients underwent colonoscopies. 55.4% of colonoscopies were performed within 24 hours of presentation. A source of LGIB was identified in 55.7% of first attempt colonoscopies. Endoscopic intervention was required in 10.9% of cases and rebleeding occurred in 24.6%, of which 6.5% required hospital re-admission. 2.7% required emergency colectomy and the calculated mortality rate was 1%. Risk ratios comparing urgent to delayed colonoscopy for source of LGIB identification, colectomy and mortality were 1.01, 4.8 and 1.2, respectively. Age and timing of colonoscopy appeared to be predictive of colectomy on regression analysis.
Conclusions:
Urgent colonoscopy for LGIB did not improve the rate of identification of the source of bleeding, colectomy rate or mortality rate and was predictive of the need for emergency colectomy.
Related Concept Videos
Endoscopic Procedures II: Colonoscopy
Lower GI Series: Barium Enema
Procedure Details
The examination begins by inserting a lubricated rectal tube into the patient's rectum to administer a radiopaque barium solution. The barium flow is carefully...
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Serum Laboratory Studies, Stool Test, Breath Test
