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FINGERPRINT SIGN OF THE HENLE FIBER LAYER.

Shane M Griffin1, H Richard McDonald2,3, Robert N Johnson2,3

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En face optical coherence tomography revealed concentric, fingerprint-like waves in the Henle fiber layer (HFL) of patients with retinal traction. This "fingerprint sign" may indicate biomechanical changes due to traction, aiding clinical decisions.

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Area of Science:

  • Ophthalmology
  • Retinal Imaging
  • Biomechanical Analysis

Background:

  • Tractional pathologies of the retina can cause significant visual impairment.
  • Understanding the biomechanical consequences of retinal traction is crucial for diagnosis and treatment.
  • The Henle fiber layer (HFL) is a distinct retinal layer susceptible to mechanical forces.

Purpose of the Study:

  • To describe the appearance of concentric, fingerprint-like waves within the Henle fiber layer (HFL).
  • To utilize en face optical coherence tomography (OCT) for visualizing these waves in patients with retinal traction.
  • To correlate OCT findings with histopathological observations of HFL waves.

Main Methods:

  • Retrospective analysis of OCT data from six eyes across six patients.
  • Volumetric OCT scans were specifically focused at the level of the HFL.
  • En face imaging was employed to visualize structures within the HFL.

Main Results:

  • Concentric, fingerprint-like waves were visualized in the HFL of all six study eyes.
  • These en face OCT findings were consistent with previously described histopathological HFL waves.
  • The observed waves appeared as hyperreflective rings within the HFL.

Conclusions:

  • Volumetric OCT can visualize en face concentric, fingerprint-like hyperreflective rings in the HFL.
  • This "fingerprint sign" may represent a biomechanical consequence of retinal traction.
  • Recognition of this sign can aid clinical decision-making in managing retinal traction.