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Cellular Angiofibroma: A Rare Vulvar Tumor Case Report
Ana Helena Barbosa Fachada1, Cátia Sofia Guilherme Ferreira Pais1, Marta Andrea Ferreira Fernandes1
1Gynecology and Obstetrics Department, Centro Hospitalar Tondela-Viseu, Viseu, Portugal.
Summary
Cellular angiofibroma (CA) is a rare vulvar tumor. Histology and immunohistochemistry are key to diagnosing CA, distinguishing it from other vulvar lesions, and ensuring a good prognosis.
Area of Science:
- Gynecologic Oncology
- Dermatopathology
- Surgical Pathology
Background:
- Cellular angiofibroma (CA) is a rare benign mesenchymal tumor predominantly affecting the vulvovaginal region in women.
- Vulvar location accounts for 70% of CA cases, presenting nonspecific clinical signs mimicking other vulvar tumors.
Observation:
- A 49-year-old woman presented with a large right vulvar mass.
- Preoperative diagnosis suggested a Bartholin cyst, a common vulvar swelling.
Findings:
- Histological and immunohistochemical examination confirmed the diagnosis of cellular angiofibroma.
- These features are crucial for differentiating CA from other vulvar neoplasms.
Implications:
- Accurate diagnosis of CA is essential for appropriate patient management and prognosis.
- Understanding CA's distinct histological profile aids in distinguishing it from malignant vulvar conditions.
