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Resolution of Recurrent Oro-facial Herpes Simplex Using a Topical Botanical Gel: A Case Report
Erik O Nelson1, Guillermo G Ruiz1, Adam F Kozin1
1Southwest College of Naturopathic Medicine, The Ric Scalzo Institute for Botanical Research, Tempe, AZ.
The Yale Journal of Biology and Medicine
|July 2, 2020
Summary
A novel botanical blend effectively treated oral herpes labialis (cold sores), reducing symptoms and duration. This treatment also decreased the frequency of future herpes simplex virus-1 outbreaks.
Area of Science:
- Dermatology
- Virology
- Herbal Medicine
Background:
- Oral herpes labialis, caused by herpes simplex virus-1 (HSV-1), presents challenges in management due to limited efficacy of current treatments.
- Existing therapies, including prescription drugs and over-the-counter agents like docosanol, offer only partial relief from pain and lesion duration, and do not prevent recurrence.
Observation:
- A case report details the treatment of oro-facial herpes labialis using a synergistic botanical blend.
- The treatment demonstrated a significant reduction in lesion symptoms and pain scores.
Findings:
- The botanical blend successfully reduced lesion duration and associated pain.
- Post-treatment monitoring and application during prodromal symptoms indicated a reduction in the frequency of subsequent outbreaks.
Implications:
- This botanical blend shows promise for both acute and prodromal treatment of oro-facial herpes infections.
- The findings suggest a potential for this treatment to reduce the recurrence rate of herpes labialis.

