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Updated: Dec 16, 2025

Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line
Published on: September 28, 2022
Case Report: Brachial Neuritis in a Patient with Epstein Barr Virus
Acute Epstein Barr virus infection can cause persistent neurological symptoms, including limb weakness, even when initial cerebrospinal fluid tests are negative. This highlights the importance of considering EBV in unexplained neurological presentations.
Area of Science:
- Neurology
- Infectious Diseases
- Virology
Background:
- Epstein Barr virus (EBV) is a common human herpesvirus.
- Neurological manifestations of EBV are reported but may be underdiagnosed.
- Acute EBV infection can present with diverse clinical symptoms.
Purpose of the Study:
- To report a case of persistent neurological sequelae following acute Epstein Barr virus infection.
- To highlight the diagnostic challenges and underestimation of neurological involvement in EBV infections.
Main Methods:
- Case report of a 41-year-old male with recent travel history.
- Clinical presentation including fever, coryzal symptoms, shoulder pain, and weakness.
- Laboratory investigations including liver function tests and electromyography.
- Cerebrospinal fluid analysis.
Main Results:
- The patient presented with symptoms suggestive of acute EBV infection.
- Electromyography revealed abnormalities in the right upper limb.
- Cerebrospinal fluid analysis was negative for EBV.
- Persistent right upper limb weakness was noted at three-month follow-up.
Conclusions:
- Acute Epstein Barr virus infection can lead to prolonged neurological deficits.
- Neurological complications of EBV may occur despite negative cerebrospinal fluid findings.
- EBV should be considered in the differential diagnosis of unexplained neurological symptoms.
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