Related Experiment Videos
Inherited Xq duplication due to a zygotic translocation t(X;X)(q23;q27)
N Morichon-Delvallez1, J Couturier, V Bourdrel
1Laboratoire de Cytogénétique, Centre Hospitalier Régional et Universitaire, Amiens.
Annales De Genetique
|January 1, 1988
Abstract:
An Xq-duplication was found in a female child with multiple malformations. The family study revealed that her mother, who has a nearly normal phenotype, carries the same duplication. The karyotype of the grandmother shows the existence of a mosaicism: 46,X,del(X) (q23)/46,X,dup(X)(q27----q23). This mosaicism can be related to a translocation t(X;X)(q23;q27) during the first cell division of the zygote.