Recent Developments in Endoscopic Endonasal Approach for Pituitary Adenomas
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Updated: Dec 16, 2025

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Jitin Bajaj1, P Sarat Chandra2
1Department of Neurosurgery, Superspeciality Hospital, NSCB Medical College, Jabalpur, MP, India.
Background:
Endoscopic endonasal transsphenoidal approach has become the workhorse for pituitary adenomas. The residual rates and complications continue to present as challenges for the pituitary surgeons.
Objective:
To review the recent developments in endoscopic pituitary surgeries for improving patient outcomes and safety rates.
Methodology:
A search of the last ten years, on PubMed and Google Scholar was performed with the keywords "Pituitary and Neuroendoscopy". A total of 345 articles were found (44 review, 193 original). Relevant articles were chosen.
Results:
Substantial improvement has taken place in the field of endoscopic pituitary surgery in the last decade. These include 3D printing, 3D endoscopes, 3D neuronavigation, multi-modal neuronavigation, ultra-high-definition endoscopes, optical fluorescence agents, intraoperative MRI, to name a few.
Conclusion:
The technological advancements have increased the resection rates, improved patient outcomes, and helped in the training of younger surgeons. A higher cost remains a concern.

