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Coronavirus disease 2019 (COVID-19): an evidence map of medical literature

Nan Liu1,2, Marcel Lucas Chee3, Chenglin Niu4

  • 1Duke-NUS Medical School, National University of Singapore, Singapore, Singapore. liu.nan@duke-nus.edu.sg.

BMC Medical Research Methodology
|July 4, 2020
PubMed

Insights

Early COVID-19 research, primarily from Asia, focused on clinical features. Key research gaps include mental health, AI applications, and indirect patient care impacts, highlighting areas for global research prioritization.

Area of Science:

  • Medical Literature Analysis
  • Bibliometrics
  • Public Health Research

Background:

  • The COVID-19 outbreak has spurred a massive increase in medical literature since December 2019.
  • Identifying trends and knowledge gaps in early COVID-19 research is crucial for effective research prioritization and policy development.
  • Understanding these dynamics is vital for managing the current pandemic and preparing for future global health crises.

Purpose of the Study:

  • To analyze the early COVID-19 medical literature (January 1 - March 24, 2020).
  • To identify cross-sectional and longitudinal trends in COVID-19 research.
  • To systematically uncover underexplored research areas and knowledge gaps.

Main Methods:

  • Searched PubMed and Embase for COVID-19 literature.
  • Utilized evidence maps and bibliometric analyses to characterize literature growth.
  • Examined trends in publication focus, international collaboration, and publication speed.

Main Results:

  • Early COVID-19 literature predominantly originated from Asia, focusing on clinical features and diagnosis.
  • Significant research gaps exist in areas like mental health, AI, pathophysiology, and indirect care impacts.
  • International research collaboration was limited (24.7%), with a median publication time of 8 days.

Conclusions:

  • Despite a high volume of early publications, substantial knowledge gaps persist in COVID-19 research.
  • The findings highlight critical areas for future research prioritization and policy planning.
  • This analysis provides valuable insights for the global research community to address the pandemic and future health crises.
Abstract

Keywords:
COVID-19CoronavirusEvidence gap mapReviewSARS-CoV-2

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