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Updated: Dec 16, 2025

Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice
Published on: September 28, 2015
[Research Advances in the Association between Inflammasome and Abdominal Aortic Aneurysm]
Lei Ji1, Fangda Li1, Yuehong Zheng1
1Department of Vascular Surgery,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
Abstract:
The inflammasome is a multiprotein complex localized in the cytoplasm.It can mediate the expressions of various inflammatory cytokines such as interleukin(IL)-1β and IL-18 and plays a key role in regulating inflammatory response.As sterile inflammation,abdominal aortic aneurysm currently can only be treated by surgery.This article reviews the research advances in the role of inflammasomes in abdominal aortic aneurysm.
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