Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

In Vitro Fertilization01:24

In Vitro Fertilization

753
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
753
Ovarian Cycle01:27

Ovarian Cycle

3.0K
The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle...
3.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Early real-world effectiveness of mirikizumab in a difficult-to-treat ulcerative colitis cohort.

Gastroenterologia y hepatologia·2026
Same author

Clinical Outcomes and Predictors of Adverse Events in Influenza Patients Managed in a Hospital-at-Home Program: A 10-Year Retrospective Study.

American journal of medicine open·2026
Same author

Response to: Clarifying Molecular Specificity and Outcome Definitions in Progestogen Route Meta-Analysis.

Reproductive biomedicine online·2026
Same author

Transcriptional states define dependencies and therapeutic vulnerabilities in head and neck cancer.

NPJ precision oncology·2026
Same author

Perivascular adipose tissue modulates aortic reactivity in Marfan syndrome mice in a sex- and region-specific manner: Redox-dependent anticontractile effects in the female ascending aorta.

Biochemical pharmacology·2026
Same author

Assessing the role of community pharmacists in early skin cancer detection: a real-world study.

Scientific reports·2026

Related Experiment Video

Updated: Dec 16, 2025

Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model
06:49

Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model

Published on: April 7, 2023

2.1K

Progesterone use in assisted reproductive technology.

Elena Labarta1, Cristina Rodríguez2

  • 1Human Reproduction Department, IVI-RMA Valencia, Plaza Policía Local, 3, 46015, Spain; IVI RMA Foundation, Research, Valencia, Spain.

Best Practice & Research. Clinical Obstetrics & Gynaecology
|July 4, 2020
PubMed
Summary

Progesterone supplementation is crucial for luteal phase support in assisted reproduction to enhance pregnancy outcomes. Individualizing progesterone protocols is key for optimizing results in embryo transfer cycles.

Keywords:
Assisted reproductive technologyLive birthLuteal phase supportPregnancyProgesterone

More Related Videos

Author Spotlight: Inducing Pseudopregnancy in Female Mice Without the Need for Vasectomized Males Prior to Non-Surgical Embryo Transfer or Artificial Insemination
05:36

Author Spotlight: Inducing Pseudopregnancy in Female Mice Without the Need for Vasectomized Males Prior to Non-Surgical Embryo Transfer or Artificial Insemination

Published on: July 7, 2023

9.5K
Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy
09:03

Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy

Published on: August 25, 2019

9.8K

Related Experiment Videos

Last Updated: Dec 16, 2025

Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model
06:49

Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model

Published on: April 7, 2023

2.1K
Author Spotlight: Inducing Pseudopregnancy in Female Mice Without the Need for Vasectomized Males Prior to Non-Surgical Embryo Transfer or Artificial Insemination
05:36

Author Spotlight: Inducing Pseudopregnancy in Female Mice Without the Need for Vasectomized Males Prior to Non-Surgical Embryo Transfer or Artificial Insemination

Published on: July 7, 2023

9.5K
Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy
09:03

Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy

Published on: August 25, 2019

9.8K

Area of Science:

  • Reproductive Endocrinology
  • Obstetrics & Gynecology
  • Assisted Reproductive Technology

Background:

  • Progesterone is essential for uterine preparation and pregnancy maintenance during the luteal phase.
  • Luteal phase deficiency is common in assisted reproduction treatments, impacting implantation and ongoing pregnancy rates.
  • Exogenous progestogens are widely used for luteal phase support due to proven efficacy and safety.

Purpose of the Study:

  • To review the role and administration of progesterone for luteal phase support in various embryo transfer scenarios.
  • To discuss current evidence and best practices for progesterone supplementation in stimulated, artificial, and natural cycles.
  • To highlight the importance of individualized luteal phase support strategies.

Main Methods:

  • Comprehensive literature review of studies on progesterone and luteal phase support.
  • Analysis of progesterone
  • administration protocols in different assisted reproduction settings.

Main Results:

  • Exogenous progestogens are the primary method for luteal phase support in assisted reproduction.
  • Progesterone supplementation is necessary to improve implantation and pregnancy rates in cases of luteal phase deficiency.
  • No single 'perfect' protocol exists; patient-specific needs should guide treatment.

Conclusions:

  • Luteal phase support with progesterone is a critical component of assisted reproduction.
  • Individualized progesterone protocols are recommended to optimize outcomes in embryo transfer cycles.
  • Further research may refine personalized luteal phase support strategies.